Primary Objective

To assess the outcomes of patients with Richter’s Transformation with CNS involvement.

Secondary Objectives

• Assess treatment outcomes in cases of RS-CNS
• Assess survival in cases of RS-CNS
• Identify mutation profile of RS-CNS
• Identify prognostic markers of patients with RS-CNS

Update 19 February 2026 – Only a handful of patients in, data in and will draft something shortly